In Scooby-Doo 2: Monsters Unleashed, someone has brought the costumes belonging to Scoobys greatest nemesis to life and now they are threatening all of Coolsville. Join Scooby, Shaggy, Fred and the rest of the Scooby-Doo Gang as they team up to solve the mystery and save Coolsville. During the game you control Scooby, Daphne and the whole Scooby gang as they run, jump and battle their way post scores of frightening creatures. On each level you have specific objectives that you must achieve in addition to collecting Scooby Snacks and other powerups. Scooby-Doo 2 Monsters Unleashed is a single-player action/adventure that utilizes a password feature for marking your progress in the game.

Offering the game version of the movie SCOOBY DOO 2: MONSTERS UNLEASHED has allowed the creators of both the movie and the game to come up with a unique bonus for fans of both. Game Boy Advance images and secret codes in the movie version can be used to get at additional game features. Another advantage is that each player who completes the entire game can repeat all of the mini-games and battle enemies one by one in special fights. Other features to look forward to in the game is to gather clues as a member of Mystery, Inc., use disguises, set traps, and dodge some of the most frightening monsters featured on the classic television show. Each game level has been created to mirror actual scenes from the move and the artwork stays true to the universal perception of Scooby Doo. The levels are fun yet not too complicated and can appeal to both adults and children.